Eurohead Project: Migraine genes and neurobiological pathways

Alternating Hemiplegia of Childhood: No Mutations in the Glutamate Transporter EAAT1.

de Vries B, Haan J, Stam AH, Vanmolkot KR, Stroink H, Laan LA, Gill DS, Pascual J, Frants RR, van den Maagdenberg AM, Ferrari MD.

Neuropediatrics 2006;37:302-4.

Association between a 19 bp deletion polymorphism at the dopamine beta-hydroxylase (DBH) locus and migraine with aura.

Fernandez F, Lea RA, Colson NJ, Bellis C, Quinlan S, Griffiths LR.

J Neurol Sci 2006;251:118-23.

The search for migraine genes: an overview of current knowledge.

Colson NJ, Fernandez F, Lea RA, Griffiths LR.

Cell Mol Life Sci 2006 Dec 22; [Epub ahead of print]

Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm the association with migraine with aura.

Kaunisto M, Kallela M, Hamalainen E, Kilpikari R, Havanka H, Harno H, Nissila M, Sako E, Ilmavirta M, Liukkonen J, Teirmaa H, Tornwall O, Jussila M, Terwilliger J, Farkkila M, Kaprio J, Palotie A, Wessman M.

Cephalalgia 2006;26:1462-72

Endothelial Nitric Oxide Synthase (Glu298Asp) Polymorphism is an Independent Risk Factor for Migraine with Aura.

Borroni B, Rao R, Liberini P, Venturelli E, Cossandi M, Archetti S, Caimi L, Padovani A.

Headache 2006;46:1575-9

Validation of the deCODE Migraine Questionnaire (DMQ3) for use in genetic studies.

Kirchmann M, Seven E, Bjornsson A, Bjornssdottir G, Gulcher JR, Stefansson K, Olesen J.

Eur J Neurol 2006;13:1239-44

Variation of the serotonin transporter gene SLC6A4 in the susceptibility to migraine with aura.

Todt U, Freudenberg J, Goebel I, Heinze A, Heinze-Kuhn K, Rietschel M, Gobel H, Kubisch C.

Neurology 2006;67:1707-9

Intravital microscopy on a closed cranial window in mice: a model to study trigeminovascular mechanisms involved in migraine.

Gupta S, Akerman S, van den Maagdenberg AM, Saxena PR, Goadsby PJ, van den Brink AM.

Cephalalgia 2006;26:1294-303

The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with migraine without aura.

Mazaheri S, Hajilooi M, Rafiei A. J Neurol 2006 Oct 24;

[Epub ahead of print]

A genetic association study of dopamine metabolism-related genes and chronic headache with drug abuse.

Cevoli S, Mochi M, Scapoli C, Marzocchi N, Pierangeli G, Pini LA, Cortelli P, Montagna P.

Eur J Neurol 2006;13:1009-13.

NF-kappaB activity and iNOS expression in monocytes from internal jugular blood of migraine without aura patients during attacks.

Sarchielli P, Floridi A, Mancini ML, Rossi C, Coppola F, Baldi A, Pini LA, Calabresi

P. Cephalalgia 2006;26:1071-9

Serotonin in trigeminal Ganglia of female rodents: relevance to menstrual migraine.

Berman NE, Puri V, Chandrala S, Puri S, Macgregor R, Liverman CS, Klein RM.

Headache 2006;46:1230-45.

Imaging abnormalities in sporadic hemiplegic migraine on conventional MRI, diffusion and perfusion MRI and MRS.

Jacob A, Mahavish K, Bowden A, Smith ET, Enevoldson P, White RP.

Cephalalgia 2006;26:1004-9.

Relation of atrial shunts to migraine in patients with ischemic stroke and peripheral emboli.

Wilmshurst P, Nightingale S, Pearson M, Morrison L, Walsh K.

Am J Cardiol 2006;98:831-3.

Tissue injury regulates serotonin 1D receptor expression: implications for the control of migraine and inflammatory pain.

Ahn AH, Basbaum AI.

J Neurosci 2006;26:8332-8

Medication-overuse headache in patients with cluster headache.

Paemeleire K, Bahra A, Evers S, Matharu MS, Goadsby PJ.

Neurology 2006;67:109-13

Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4.

von Brevern M, Ta N, Shankar A, Wiste A, Siegel A, Radtke A, Sander T, Escayg A.

Headache 2006;46:1136-41

Genetic biomarkers for migraine.

De Vries B, Haan J, Frants RR, Van den Maagdenberg AM, Ferrari MD.

Headache 2006;46:1059-68

New insights into migraine pathophysiology.

Sanchez-Del-Rio M, Reuter U, Moskowitz MA.

Curr Opin Neurol 2006;19:294-8

Delayed upregulation of ATP P2X3 receptors of trigeminal sensory neurons by calcitonin gene-related peptide.

Fabbretti E, D'Arco M, Fabbro A, Simonetti M, Nistri A, Giniatullin R.

J Neurosci 2006;26:6163-71.

Characterisation of CGRP receptors in the human isolated middle meningeal artery.

Gupta S, Mehrotra S, Avezaat CJ, Villalon CM, Saxena PR, Maassenvandenbrink A

Life Sci 2006;79:265-71.

Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine.

Vanmolkot KR, Kors EE, Turk U, Turkdogan D, Keyser A, Broos LA, Kia SK, van den Heuvel JJ, Black DF, Haan J, Frants RR, Barone V, Ferrari MD, Casari G, Koenderink JB, van den Maagdenberg AM.

Eur J Hum Genet 2006;14:555-60

No association of C-1019G promoter polymorphism of 5-HT1A receptor gene with migraine.

Yang XS, Xu XP, Yang QD.

Eur J Neurol 2006;13:533-5.

Diffusion tensor magnetic resonance imaging at 3.0 tesla shows subtle cerebral grey matter abnormalities in patients with migraine.

Rocca MA, Ceccarelli A, Falini A, Tortorella P, Colombo B, Pagani E, Comi G, Scotti G, Filippi M.

J Neurol Neurosurg Psychiatry 2006;77:686-9.

Haplotype-based systematic association studies of ATP1A2 in migraine with aura.

Netzer C, Todt U, Heinze A, Freudenberg J, Zumbroich V, Becker T, Goebel I, Ohlraun S, Goebel H, Kubisch C.

Am J Med Genet B Neuropsychiatr Genet 2006;141:257-60.

Minor head trauma-induced sporadic hemiplegic migraine coma.

Curtain RP, Smith RL, Ovcaric M, Griffiths LR.

Pediatr Neurol 2006;34:329-32.

Field testing alternative criteria for chronic migraine

Bigal ME, Tepper SJ, Sheftell FD, Rapoport AM, Lipton RB.

Cephalalgia 2006;26:477-82.

Basilar-type migraine: clinical, epidemiologic, and genetic features.

Kirchmann M, Thomsen LL, Olesen J.

Neurology 2006;66:880-6

A novel ATP1A2 mutation in a family with FHM type II.

Pierelli F, Grieco GS, Pauri F, Pirro C, Fiermonte G, Ambrosini A, Costa A, Buzzi MG, Valoppi M, Caltagirone C, Nappi G, Santorelli FM.

Cephalalgia 2006;26:324-8.

Endothelin receptor A -231 G>A polymorphism: no linkage to primary pediatric headache.

Lisi V, Garbo G, Battistella P, Micciche F, Stecca A, Terrazzino S, Franzoi M, Tripoli E, Leon A, Clementi M.

Headache 2006;46:486-91

The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura.

Kirchmann M, Thomsen LL, Olesen J.

Am J Med Genet B Neuropsychiatr Genet. 2006 Feb 28; [Epub ahead of print]

Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation.

Vanmolkot KR, Stroink H, Koenderink JB, Kors EE, van den Heuvel JJ, van den Boogerd EH, Stam AH, Haan J, De Vries BB, Terwindt GM, Frants RR, Ferrari MD, van den Maagdenberg AM.

Ann Neurol 2006;59:310-4.

Early onset, non fluctuating spinocerebellar ataxia and a novel missense mutation in CACNA1A gene.

Tonelli A, D'Angelo MG, Salati R, Villa L, Germinasi C, Frattini T, Meola G, Turconi AC, Bresolin N, Bassi MT.

J Neurol Sci. 2006;241:13-7.

Effects of a website designed to improve the management of migraines.

Sciamanna CN, Nicholson RA, Lofland JH, Manocchia M, Mui S, Hartman CW.

Headache 2006;46:92-100.

Association of migraine and ESR1 G325C polymorphism.

Oterino A, Pascual J, Ruiz de Alegria C, Valle N, Castillo J, Bravo Y, Gonzalez F, Sanchez-Velasco P, Cayon A, Leyva-Cobian F, Alonso-Arranz A, Munoz P.

Neuroreport 2006;17:61-4.

Suppression of cortical spreading depression in migraine prophylaxis.

Ayata C, Jin H, Kudo C, Dalkara T, Moskowitz MA.

Ann Neurol 2006 Jan 31; [Epub ahead of print]